An Insight into Ophthalmic Drug Delivery System
نویسندگان
چکیده
منابع مشابه
An Insight to Ophthalmic Drug Delivery System
Treating various ailments of eye utilizes mostly two strategies i.e. delivery of the therapeutic agent by development of a novel delivery system or by enhancing the permeation of therapeutically active agent by the use of penetration enhancers or by the alteration of its physicochemical properties. Conventional ophthalmic drugs delivery system including eye drops, ointments and gels, are no lon...
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Promising management of eye ailments take off effective concentration of drug at the eye for sufficient period of time. Ocular drug delivery is hampered by the barriers protecting the eye. The bioavailability of the active drug substance is often the major hurdle to overcome. Conventional ocular dosage form, including eye drops, are no longer sufficient to combat ocular diseases. This article r...
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In the present update on ocular drug delivery system, particulate carrier, the tremendous advances in ocular drug delivery system, the polymers used in particulate carriers for ocular dosage forms, the use of drug complexes and other technological advances are discussed. This review focuses on recent literature regarding mucoadhesive particulate dosage forms with special attention to in vivo st...
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Various strategies for ocular drug delivery are considered; from basic formulation techniques for improving availability of drugs; viscosity enhancers and mucoadhesives aid drug retention and penetration enhancers promote drug transport into the eye. The use of drug-loaded contact lenses and ocular inserts allows drugs to be better placed where they are needed for more direct delivery. Developm...
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Topical route of administration is the most commonly used method for the treatment of ophthalmic diseases. However, presence of several layers of permeation barriers starting from the tear film till the inner layers of cornea make it difficult to achieve the therapeutic concentrations in the target tissue within the eye. In order to circumvent these barriers and to provide sustained and targete...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutical Sciences and Drug Research
سال: 2009
ISSN: 0975-248X
DOI: 10.25004/ijpsdr.2009.010101